The role of myeloperoxidase and myeloperoxidase–antineutrophil cytoplasmic antibodies (MPO-ANCAs) in the pathogenesis of human MPO-ANCA-associated glomerulonephritis
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چکیده
منابع مشابه
A case of myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA)-associated glomerulonephritis and concurrent membranous nephropathy
BACKGROUND Myeloperoxidase anti-neutrophil cytoplasmic antibody-associated glomerulonephritis (MPO-ANCA-GN) and concurrent membranous nephropathy (MN) are very rare combination. Their causal relationship has been suggested, but not determined. CASE PRESENTATION A 73-years-old male with 5-year history of proteinuria underwent an operation for his sigmoid colon cancer. Seven months later, he wa...
متن کاملEvaluation of antibodies against human HSP60 in patients with MPO-ANCA associated glomerulonephritis: a cohort study
BACKGROUND Human Heat Shock Protein 60 (hHSP60) has been implicated in autoimmunity through molecular mimicry, based on the high degree of homology with HSP65 of micro-organisms leading to autoimmune recognition of the human protein. Additionally, sequence homology between hHSP60 and myeloperoxidase (MPO) has been described. MPO is a major autoantigen in vasculitis associated with antineutrophi...
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از محوری ترین اثراتی که یک فیلم سینمایی ایجاد می کند دیالوگ هایی است که هنرپیش گان فیلم میگویند. به زعم یک فیلم ساز, یک شیوه متأثر نمودن مخاطب از اثر منظوره نیروی گفتارهای گوینده, مثل نیروی عاطفی, ترس آور, غم انگیز, هیجان انگیز و غیره, است. این مطالعه به بررسی این مسأله مبادرت کرده است که آیا نیروی فراگفتاری هنرپیش گان به مثابه ی اعمال گفتاری در پنج فیلم هالیوودی در نسخه های دوبله شده باز تولید...
15 صفحه اولChlamydia pneumoniae infection and MPO-ANCA-associated glomerulonephritis.
Sir, Many patients on chronic haemodialysis (HD) suffer from chronic eye diseases, and the interaction of these diseases with the dialysis procedure can lead to worsening of vision [1]. Different studies have emphasized the effect of HD on visual acuity (VA), ocular surface disorders and tear function changes, fundus changes, VEP parameters, visual field findings and contrast sensitivity [2–5]....
متن کاملMPO-C-ANCA-associated necrotising and crescentic glomerulonephritis
The patterns of ANCA staining usually relate closely to antibodies against myeloperoxidase and proteinase-3. C-ANCA is mainly antibodies to proteinase-3 and P-ANCA is antibodies to myeloperoxidase. C-ANCA with antibodies to MPO with clinical sequelae is unusual.
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ژورنال
عنوان ژورنال: Clinical and Experimental Nephrology
سال: 2013
ISSN: 1342-1751,1437-7799
DOI: 10.1007/s10157-013-0787-7